Korean J Ophthalmol > Volume 3(2); 1989 > Article
Korean Journal of Ophthalmology 1989;3(2):85-89.
DOI: https://doi.org/10.3341/kjo.1989.3.2.85    Published online December 30, 1989.
Prognostic comparison of Behcet's disease with or without HLA-Bw 51 antigen.
Man Soo Kim, Jae Ho Kim
Department of Ophthalmology, Kangnam St Mary's Hospital, Catholic University Medical College, Seoul, Korea.
Abstract
To know the prognosis of Behcet's disease with HLA-Bw 51 antigen, comparison studies of 24 cases of Behcet's disease were investigated. The sex distribution was 14 males (58%) and 10 females (42%). The patients were grouped into three clinical types: the complete type with 11 cases (45%), the incomplete type with eight cases (33%) and the suspect type with five cases (22%), according to the criteria established by the Behcet's Disease Research Committee in Japan (1982). They were also divided into three ocular types according to the location of the inflammation: the anterior segment type, the fundus type and the mixed type. They were divided into 10%, 10% and 60% in HLA-Bw 51 negative group and 14%, 22% and 64% in HLA-Bw 51 positive group, respectively. Skin lesions observed in 30% of the HLA-Bw 51 negative group and 70% of the HLA-Bw 51 positive group, which was statistically significant (p < 0.01). The other general symptoms and the visual acuity between the two groups were not statistically significant (p > 0.1).
Key Words: Behcet's disease;HLA-Bw 51;visual acuity;prognosis
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