Effects of sodium hyaluronate on filtration bleb in rabbits.

Hyung,  Sung Min; Kim,  Dong Myung; Hong,  Chul; Youn,  Dong Ho

doi:1993.7.1.11

Korean J Ophthalmol > Volume 7(1); 1993 > Article

Research Support, Non-U.S. Gov't

Korean Journal of Ophthalmology 1993;7(1):11-15.
DOI: https://doi.org/10.3341/kjo.1993.7.1.11 Published online June 30, 1993.

Effects of sodium hyaluronate on filtration bleb in rabbits.

Sung Min Hyung, Dong Myung Kim, Chul Hong, Dong Ho Youn

¹Department of Ophthalmology, College of Medicine, Chungbuk National University, Cheongju, Chungbuk, Korea.
²Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.
³Department of Ophthalmology, College of Medicine, Chungbuk National University, Cheongju, Korea.
⁴Glaucoma Service, Dr. Hong's Eye Clinic, Seoul, Korea.

Abstract

Sodium hyaluronate can be used during a trabeculectomy to prevent early postoperative hypotony and shallow anterior chamber. To determine its long-term effect on the outcome of filtration surgery, fifteen rabbits underwent a osterior-lip sclerectomy in both eyes. Into their right eyes 0.2ml sodium hyaluronate, and into left eyes 0.2ml balanced salt solution were injected intracamerally. Gross and histopathological differences of bleb were observed. There was no statistically significant difference in longevity of the filtration bleb.

Key Words: filtration bleb;hypotony;Sodium hyaluronate;posterior-lip sclerectomy;rabbits