Korean J Ophthalmol > Epub ahead of print
DOI: https://doi.org/10.3341/kjo.2021.0076    [Epub ahead of print]
Published online July 8, 2021.
Agreement between Scheimpflug camera and the swept-source optical coherence tomography measurements in keratometry and higher-order aberrations
Yujin Gim1, Roo Min Jun2, Kyung Eun Han1
1The Institute of Ophthalmology and Optometry, Department of Ophthalmology, Ewha Womans University College of Medicine, Mokdong Hospital, Seoul, South Korea
2The Institute of Ophthalmology and Optometry, Department of Ophthalmology, Ewha Womans University College of Medicine, Seoul Hospital, Seoul, South Korea
Correspondence:  Kyung Eun Han, Tel: +82-2-2650-5154, Fax: +82-2654-4334, 
Email: hanke@ewha.ac.kr
Received: 14 May 2021   • Revised: 25 June 2021   • Accepted: 30 June 2021
To evaluate the compatibility of corneal curvature and astigmatism, and higher-order aberrations (HOAs) measured by the Scheimpflug camera Pentacam HR and the swept-source optical coherence tomography ANTERION.
This prospective study included normal subjects with no ophthalmic history. Steep keratometry (K), flat K, astigmatism and its axis of the anterior and posterior surfaces, total corneal power, and HOAs using the two instruments were compared. To compare the mean values of the measurements, a paired t-test was used. Bland–Altman analysis was applied to assess the agreement between the two devices.
Fifty-three eyes of 53 subjects were evaluated. There were statistically significant differences for steep K, astigmatism, and vector J0, J45 in the anterior surface and total corneal power between the two devices (p<0.05). There were also significant differences in the most of the keratometric values of the posterior corneal surface (p<0.05) except J0 (p=0.410). Both devices showed strong positive correlations in Ks, Kf, Kastig (r>0.81, p<0.001) with wide ranges of a 95% limit of agreement (LoA). Vectoral components were significantly correlated (r>0.78, p<0.001) with narrow 95% LoA, except J45 of the posterior surface (r=0.39, p=0.004). In the corneal HOAs, there were statistically significant differences in the vertical coma, horizontal trefoil, spherical aberration, and root mean square (RMS) of each fifth- and sixth-order Zernike coefficient (p=0.043, 0.041, p<0.001, p<0.001, and p<0.001, respectively). Other HOAs showed moderate to strong positive correlations (r>0.37, p<0.05). Most HOAs, except for the horizontal trefoil, showed clinically acceptable agreements. The total RMS of HOAs was not significantly different between the two devices (p=0.122).
Most of the keratometric values cannot be used interchangeably. However, the vectoral component of astigmatism showed clinically good agreement. Several HOAs have statistically significant differences; however, almost all HOAs showed acceptable agreements, except for the horizontal trefoil.
Key Words: Keratometry, Total corneal power, Higher-order aberration, swept-source optical coherence tomography, Scheimpflug camera
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